Dioxin exposure and porcine reproductive hormonal activity
نویسندگان
چکیده
منابع مشابه
Dioxin exposure and porcine reproductive hormonal activity Exposição à dioxina e atividade hormonal reprodutiva porcina
To characterize the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD) during both the follicular and luteal phases of the ovarian cycle, the direct effect of TCDD was investigated in vitro using a system of primary monolayer cell culture. Granulosa and theca cells were collected from the preovulatory follicles and cultured as a co-culture, thus resembling follicles in vivo. Luteal cells wer...
متن کاملHuman exposure to dioxin.
Because 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is the most potent chemical carcinogen evaluated by the U.S. Environmental Protection Agency (EPA), many people fear that exposure to even small amounts of TCDD could lead to serious health effects. Ambient measurements confirm that environmental TCDD contamination is widespread. The public is concerned about TCDD exposure from such diverse sou...
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Dioxin-related compounds are associated with teratogenic and mutagenic risks in laboratory animals, and result in adverse pregnancy outcomes. However, there were inconsistent results in epidemiology studies. In view of this difference, we conducted a systematic review and meta-analysis to examine this association and to assess the heterogeneity among studies. Comprehensive literature searches w...
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ژورنال
عنوان ژورنال: Cadernos de Saúde Pública
سال: 2002
ISSN: 0102-311X
DOI: 10.1590/s0102-311x2002000200010